AS Monaco FC vs Tottenham Hotspur F.C. Prediction 22 October 2025

Monaco remain a consistent top-third side in Ligue 1, recently drawing 2–2 with Angers. The Red and Whites made an emergency coaching change last week, and their European campaign has started slowly — just one point from two matches: a heavy 1–4 loss to Club Brugge and a 2–2 draw with Manchester City.

Tottenham, on the other hand, edged Villarreal 1–0 and battled to a 2–2 draw against Bodø/Glimt. Spurs look a far more cohesive and confident unit than last season, and even their recent 1–2 Premier League defeat to Aston Villa hasn’t disrupted their solid form in the world’s richest league.

Three weeks ago, Monaco managed to halt Manchester City’s charge at home, and there’s reason to believe they can do the same against a less formidable Spurs side under similar conditions. For Tottenham, even securing a draw in the Principality would count as a positive result.

Monaco not to lose (1X) 1.64