SSC Napoli vs Pisa SC Prediction 21 September 2025
Added on 20 September, 2025
The final match of Serie A’s fourth round will take place on Monday evening, as reigning champions Napoli host newly-promoted Pisa in what promises to be a clash of contrasting ambitions.
Napoli have started the season in imperious form, securing the maximum nine points from their first three fixtures. With a 6-1 goal difference, Luciano Spalletti’s side currently lead the standings. The Partenopei have combined efficiency with attacking flair, registering wins over Cagliari (1-0), Sassuolo (2-0), and Fiorentina (3-1). Their blend of tactical discipline, quick transitions, and clinical finishing has allowed them to dominate matches without necessarily relying on high-scoring affairs.
Pisa, meanwhile, have returned to Italy’s top flight after nearly three decades away and are still finding their feet. So far, the newly promoted side have collected just one point, drawing with Atalanta (1-1) and narrowly losing to Roma (0-1) and Udinese (0-1). The Towers have fully embraced the underdog role, relying on a compact, defensive style to frustrate opponents. Survival in Serie A will be their primary objective this season, and experience, squad depth, and defensive organization will be key factors in achieving it.
Given the disparity in quality between the two sides, Napoli are clear favorites heading into this fixture. While the Partenopei are likely to dominate possession and create multiple opportunities, Pisa’s tendency to sit deep and defend in numbers suggests that a high-scoring game is unlikely. Expect Napoli to control the tempo, patiently break down the visitors’ defensive lines, and aim to secure another routine victory as they continue their quest to defend the title.
Napoli to win and under 3.5 goals in the match 1.83