AFC Ajax vs Inter Milan Prediction 17 September 2025

Ajax came agonizingly close to the Eredivisie title last season but squandered an eight-point advantage in the final four rounds. In the new campaign, the Red and Whites have looked solid at home, defeating Telstar (2:0), Heracles (2:0), and Zwolle (3:1), though their away form has been less convincing with draws against Go Ahead Eagles (2:2) and Volendam (1:1).

Inter, meanwhile, opened their Serie A season with an emphatic 5:0 win over Torino, only to follow it with narrow defeats to Udinese (1:2) and Juventus (3:4). The Nerazzurri, last season’s Champions League finalists, are still haunted by that crushing 0:5 loss to PSG, a result the club would rather forget.

On paper, Inter boast the stronger squad and greater individual talent, yet Ajax’s home advantage and attacking style make them more than capable of putting up a fight. Both sides have the weapons to trouble each other, and this matchup looks primed for goals on both ends with the outcome difficult to predict.

Both teams to score 1.63